Five years prior everyone in Ōtsuka village died from a plague, but there were 3 survivors, Shino Inuzuka, Sosuke Inukawa and Hamaji. They take shelter in a church in a nearby village, which borders a dark and dangerous forest. The church, as well as the survivors, are viewed with suspicion by the villagers. The Imperial Church comes in search of "Murasame" the demon blade that contains "life", which Shino possesses.