In the year 2011, humans begin to manifest psychokinetic powers, leaving a trail of death and destruction in their wake. 1,000 years later, Saki Watanabe finally has her own Cantus powers awakened, and after a ritual of passage, she leaves Harmony School and joins her friends whose powers emerged earlier at the Sage Academy. However, one of them, Reiko Amano, is revealed to have weaker control over her powers than her peers, and soon afterwards she mysteriously disappears.