When Ghosts attack President Spheros, Dr. Buttocks possesses him as part of Betrayus' plot to find the repository that is holding Betrayus' body. Pac-Man and his friends go to see Sir Cumference and get a Paco-Strobo-Cacophonater. The possessed President Spheros makes everyone hate Pac-Man and Pac finds out he's been possessed. He makes Pac give him the berries and it is actually the Paco-Strobo-Cacophonater which gets Dr. Buttocks out of President Spheros' body.