After Spider-Man deals with the Crimson Dynamo, Nozomu gives the biocode installer to Akira and Hikaru, urging them to escape with Spider-Man to the heliport via an escape route, where they run into Edward, Chris, and Jessica. Meanwhile, as the other superheroes try to deal with the crisis on the island, S.H.I.E.L.D. headquarters is also attacked by supervillains, prompting Nick Fury to step into action...