Edward and Alphonse battle the new homunculus known as Wrath, who wants the rest of Edward's body to make himself human. Izumi interrupts the fight by separating the combatants with a deep chasm. After Wrath escapes, Izumi sends Edward and Alphonse to meet her alchemy teacher, an old woman named Dante, to learn an important lesson about the principle of equivalent exchange. At Dante's house, they discover that Lyra has become her apprentice, and Greed's party comes and battle the Elrics.