In Egypt, Speed Racer meets a scientist named Digger O. Bone who asks him with his dying breath to take care of his daughter Calcia. Unfortunately for Speed, Calcia has hit her head and thinks she is Cleopatra. Under the evil influence of Splint Femur, Calcia has kidnapped Trixie, threatening her with death. Speed must pass a series of tests, including a gladiator fight with lions and guards and retrieving a statue from the top of a pyramid while racing the clock to save Trixie...